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Efficacy of Cidofovir in a Murine Model of Disseminated Progressive Vaccinia

An animal model that mimics progressive disseminated vaccinia was elaborated. To this end nude (athymic) mice were inoculated intracutaneously with vaccinia virus in the lumbosacral area. Viral replication (DNA) in the skin was detected as early as day 2 postinfection (p.i.). Mice developed typical...

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Detalhes bibliográficos
Main Authors: Neyts, Johan, Leyssen, Pieter, Verbeken, Erik, De Clercq, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415602/
https://ncbi.nlm.nih.gov/pubmed/15155231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2267-2273.2004
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