Efficacy of 2-Amino-7-(1,3-Dihydroxy-2-Propoxymethyl)Purine for Treatment of Vaccinia Virus (Orthopoxvirus) Infections in Mice

We have previously shown that the N-7 substituted acyclic nucleoside analog 2-amino-7-[1,3-dihydroxy-2-propoxy)methyl]purine (compound S2242) is, both in vitro and in animal models, a potent inhibitor of the replication of several herpesviruses (Neyts et al., Antimicrob. Agents Chemother. 39:56–60,...

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Autors principals: Neyts, Johan, De Clercq, Erik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90244/
https://ncbi.nlm.nih.gov/pubmed/11120949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.84-87.2001
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