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High-Level Resistance to Ceftazidime Conferred by a Novel Enzyme, CTX-M-32, Derived from CTX-M-1 through a Single Asp240-Gly Substitution

A clinical strain of Escherichia coli isolated from pleural liquid with high levels of resistance to cefotaxime, ceftazidime, and aztreonam harbors a novel CTX-M gene (bla(CTX-M-32)) whose amino acid sequence differs from that of CTX-M-1 by a single Asp240-Gly substitution. Moreover, by site-directe...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Cartelle, Monica, del Mar Tomas, Maria, Molina, Francisca, Moure, Rita, Villanueva, Rosa, Bou, German
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2308-2313.2004
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