Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling

AIMS: We previously demonstrated that pharmacological activation of mitochondrial aldehyde dehydrogenase 2 (ALDH2) protects the heart against acute ischaemia/reperfusion injury. Here, we determined the benefits of chronic activation of ALDH2 on the progression of heart failure (HF) using a post-myoc...

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Detalhes bibliográficos
Main Authors: Gomes, Katia M.S., Campos, Juliane C., Bechara, Luiz R.G., Queliconi, Bruno, Lima, Vanessa M., Disatnik, Marie-Helene, Magno, Paulo, Chen, Che-Hong, Brum, Patricia C., Kowaltowski, Alicia J., Mochly-Rosen, Daria, Ferreira, Julio C.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155470/
https://ncbi.nlm.nih.gov/pubmed/24817685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu125
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