PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation

cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA function can be achieved by discrete compartmentalization of the enzyme via physical interaction with A-kinase anchoring proteins (AKAPs). Here, we investigated the role...

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Detaylı Bibliyografya
Asıl Yazarlar: Radeva, Mariya Y., Kugelmann, Daniela, Spindler, Volker, Waschke, Jens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154725/
https://ncbi.nlm.nih.gov/pubmed/25188285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106733
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