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PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation

cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA function can be achieved by discrete compartmentalization of the enzyme via physical interaction with A-kinase anchoring proteins (AKAPs). Here, we investigated the role...

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Bibliografische gegevens
Hoofdauteurs: Radeva, Mariya Y., Kugelmann, Daniela, Spindler, Volker, Waschke, Jens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154725/
https://ncbi.nlm.nih.gov/pubmed/25188285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106733
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