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PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation

cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA function can be achieved by discrete compartmentalization of the enzyme via physical interaction with A-kinase anchoring proteins (AKAPs). Here, we investigated the role...

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Hlavní autoři: Radeva, Mariya Y., Kugelmann, Daniela, Spindler, Volker, Waschke, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154725/
https://ncbi.nlm.nih.gov/pubmed/25188285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106733
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