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Histamine causes endothelial barrier disruption via Ca(2+)-mediated RhoA activation and tension at adherens junctions

During inflammation, the disruption of the endothelial barrier leads to increased microvascular permeability. Whether tension along cell junctions contributes to histamine-induced endothelial barrier disruption remains unknown. Rapid Ca(2+) influx induced by both histamine and thrombin was accompani...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Kugelmann, Daniela, Rotkopf, Lukas Thomas, Radeva, Mariya Yosifova, Garcia-Ponce, Alexander, Walter, Elias, Waschke, Jens
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125323/
https://ncbi.nlm.nih.gov/pubmed/30185878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31408-3
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