Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program

AIMS/HYPOTHESIS: PPARGC1A and PPARGCB encode transcriptional coactivators that regulate numerous metabolic processes. We tested associations and treatment (i.e. metformin or lifestyle modification) interactions with metabolic traits in the Diabetes Prevention Program, a randomised controlled trial i...

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Main Authors: Franks, Paul W., Christophi, Costas A., Jablonski, Kathleen A., Billings, Liana K., Delahanty, Linda M., Horton, Edward S., Knowler, William C., Florez, Jose C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154629/
https://ncbi.nlm.nih.gov/pubmed/24317794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3133-4
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