Variation at the Melanocortin 4 Receptor gene and response to weight-loss interventions in the Diabetes Prevention Program

OBJECTIVE: To assess associations and genotype × treatment interactions for melanocortin 4 receptor (MC4R) locus variants and obesity-related traits. DESIGN AND METHODS: Diabetes Prevention Program (DPP) participants (N=3,819, of whom 3,356 were genotyped for baseline and 3,234 for longitudinal anal...

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Autori principali: Pan, Qing, Delahanty, Linda M., Jablonski, Kathleen A., Knowler, William C., Kahn, Steven E., Florez, Jose C., Franks, Paul W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023472/
https://ncbi.nlm.nih.gov/pubmed/23512951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20459
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