The Pro12Ala variant at the peroxisome proliferator-activated receptor γ gene and change in obesity-related traits in the Diabetes Prevention Program

AIMS/HYPOTHESIS: Peroxisome proliferator-activated receptor γ (PPARγ), encoded by the PPARG gene, regulates insulin sensitivity and adipogenesis, and may bind polyunsaturated fatty acids (PUFA) and thiazolidinediones in a ligand-dependent manner. The PPARG proline for alanine substitution at positio...

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Bibliografische gegevens
Hoofdauteurs: Franks, P. W., Jablonski, K. A., Delahanty, L., Hanson, R. L., Kahn, S. E., Altshuler, D., Knowler, W. C., Florez, J. C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453532/
https://ncbi.nlm.nih.gov/pubmed/17898990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-007-0826-6
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