Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program

AIMS/HYPOTHESIS: The single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity associated gene (FTO) and the rs7566605 SNP located 10 kb upstream of the insulin-induced gene 2 gene (INSIG2) have been proposed as risk factors for common obesity. METHODS: We tested for genotype–treatm...

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Autori principali: Franks, P. W., Jablonski, K. A., Delahanty, L. M., McAteer, J. B., Kahn, S. E., Knowler, W. C., Florez, J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947367/
https://ncbi.nlm.nih.gov/pubmed/18839134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1158-x
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