Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program

AIMS/HYPOTHESIS: Wolfram syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness) is caused by mutations in the WFS1 gene. Recently, single nucleotide polymorphisms (SNPs) in WFS1 have been reproducibly associated with type 2 diabetes. We therefore examined the effects of these v...

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Auteurs principaux: Florez, J. C., Jablonski, K. A., McAteer, J., Sandhu, M. S., Wareham, N. J., Barroso, I., Franks, P. W., Altshuler, D., Knowler, W. C.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483955/
https://ncbi.nlm.nih.gov/pubmed/18060660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-007-0891-x
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