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TCF7L2 Polymorphisms and Progression to Diabetes in the Diabetes Prevention Program

BACKGROUND: Common polymorphisms of the transcription factor 7–like 2 gene (TCF7L2) have recently been associated with type 2 diabetes. We examined whether the two most strongly associated variants (rs12255372 and rs7903146) predict the progression to diabetes in persons with impaired glucose tolera...

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Detalhes bibliográficos
Main Authors: Florez, Jose C., Jablonski, Kathleen A., Bayley, Nick, Pollin, Toni I., de Bakker, Paul I.W., Shuldiner, Alan R., Knowler, William C., Nathan, David M., Altshuler, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762036/
https://ncbi.nlm.nih.gov/pubmed/16855264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa062418
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