PPARα-dependent exacerbation of experimental colitis by the hypolipidemic drug fenofibrate

Fibrates, such as fenofibrate, are peroxisome proliferator-activated receptor-α (PPARα) agonists and have been used for several decades as hypolipidemic agents in the clinic. However, contradictory observations exist on the role of fibrates in host response to acute inflammation, with unclear mechan...

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Main Authors: Qi, Yunpeng, Jiang, Changtao, Tanaka, Naoki, Krausz, Kristopher W., Brocker, Chad N., Fang, Zhong-Ze, Bredell, Bryce X., Shah, Yatrik M., Gonzalez, Frank J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154119/
https://ncbi.nlm.nih.gov/pubmed/25035112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00153.2014
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