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GC-MS metabolomics on PPARα-dependent exacerbation of colitis
Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, was found to exacerbate inflammation and tissue injury in experimental acute colitis mice. Through lipidomics analysis, bioactive sphingolipids were significantly up-regulated in the colitis group. In this study, to provide...
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| Publicado no: | Mol Biosyst |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6334306/ https://ncbi.nlm.nih.gov/pubmed/25790429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mb00048c |
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