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Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations.

The human VHL tumor suppressor gene has been implicated in the inherited disorder von Hippel-Lindau disease and in sporadic renal carcinoma. The homologous rat gene encodes a 185-amino acid protein that is 88% sequence identical to the aligned 213-amino acid human VHL gene product. When expressed in...

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保存先:
書誌詳細
主要な著者: Duan, D R, Humphrey, J S, Chen, D Y, Weng, Y, Sukegawa, J, Lee, S, Gnarra, J R, Linehan, W M, Klausner, R D
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC41537/
https://ncbi.nlm.nih.gov/pubmed/7604013
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