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Neutrophil-Mediated Phagocytic Host Defense Defect in Myeloid Cftr-Inactivated Mice
Cystic fibrosis (CF) is a common and deadly inherited disease, caused by mutations in the CFTR gene that encodes a cAMP-activated chloride channel. One outstanding manifestation of the disease is the persistent bacterial infection and inflammation in the lung, which claims over 90% of CF mortality....
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153692/ https://ncbi.nlm.nih.gov/pubmed/25184794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106813 |
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