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Generation of a conditional null allele for Cftr in mice
The Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene encodes a cAMP-regulated chloride channel that is important in controlling the exchange of fluid and electrolytes across epithelial cells. Mutation of CFTR can lead to Cystic Fibrosis (CF), the most common lethal genetic disease in...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711445/ https://ncbi.nlm.nih.gov/pubmed/18802965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20433 |
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