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Generation of Mice with a Conditional Null Allele for Wntless
The Wnt-signaling pathway is necessary in a variety of developmental processes and has been implicated in numerous pathologies. Wntless (Wls) binds to Wnt proteins and facilitates Wnt sorting and secretion. Conventional deletion of Wls results in early fetal lethality due to defects in body axis est...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689319/ https://ncbi.nlm.nih.gov/pubmed/20614471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20651 |
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