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Generation of mice with a conditional null allele of the Jagged2 gene
The Notch signaling pathway is an evolutionarily-conserved intercellular signaling mechanism, and mutations in its components disrupt embryonic development in many organisms and cause inherited diseases in humans. The Jagged2 (Jag2) gene, which encodes a ligand for Notch pathway receptors, is requir...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114645/ https://ncbi.nlm.nih.gov/pubmed/20533406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20626 |
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