Myeloid CFTR Loss-of-function Causes Persistent Neutrophilic Inflammation in Cystic Fibrosis

Persistent neutrophilic inflammation is a hallmark of cystic fibrosis (CF). However, the mechanisms underlying this outstanding pathology remain incompletely understood. Here we report that CFTR in myeloid immune cells plays a pivotal role in control of neutrophilic inflammation. Myeloid CFTR-Knocko...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Ng, Hang Pong, Jennings, Scott, Wellems, Dianne, Sun, Fei, Xu, Jie, Nauseef, William M., Wang, Guoshun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686288/
https://ncbi.nlm.nih.gov/pubmed/32531843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0520-193RR
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