Cargando...
Stable Histone Adduction by 4-Oxo-2-nonenal: A Potential Link between Oxidative Stress and Epigenetics
[Image: see text] Lipid electrophiles modify cellular targets, altering their function. Here, we describe histones as major targets for modification by 4-oxo-2-nonenal, resulting in a stable Lys modification structurally analogous to other histone Lys acylations. Seven adducts were identified in chr...
Gardado en:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151707/ https://ncbi.nlm.nih.gov/pubmed/25099620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503604t |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|