Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells

4-Oxo-2-nonenal (ONE) derived from lipid peroxidation modifies nucleophiles and transduces redox signaling by its reactions with proteins. However, the molecular interactions between ONE and complex proteomes and their dynamics in situ remain largely unknown. Here we describe a quantitative chemopro...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Sun, Rui, Fu, Ling, Liu, Keke, Tian, Caiping, Yang, Yong, Tallman, Keri A., Porter, Ned A., Liebler, Daniel C., Yang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629264/
https://ncbi.nlm.nih.gov/pubmed/28814509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000116
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