Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells

4-Oxo-2-nonenal (ONE) derived from lipid peroxidation modifies nucleophiles and transduces redox signaling by its reactions with proteins. However, the molecular interactions between ONE and complex proteomes and their dynamics in situ remain largely unknown. Here we describe a quantitative chemopro...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Sun, Rui, Fu, Ling, Liu, Keke, Tian, Caiping, Yang, Yong, Tallman, Keri A., Porter, Ned A., Liebler, Daniel C., Yang, Jing
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629264/
https://ncbi.nlm.nih.gov/pubmed/28814509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000116
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