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Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells

4-Oxo-2-nonenal (ONE) derived from lipid peroxidation modifies nucleophiles and transduces redox signaling by its reactions with proteins. However, the molecular interactions between ONE and complex proteomes and their dynamics in situ remain largely unknown. Here we describe a quantitative chemopro...

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Vydáno v:Mol Cell Proteomics
Hlavní autoři: Sun, Rui, Fu, Ling, Liu, Keke, Tian, Caiping, Yang, Yong, Tallman, Keri A., Porter, Ned A., Liebler, Daniel C., Yang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629264/
https://ncbi.nlm.nih.gov/pubmed/28814509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000116
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