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Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells
[Image: see text] Protein alkylation by 4-hydroxy-2-nonenal (HNE), an endogenous lipid derived electrophile, contributes to stress signaling and cellular toxicity. Although previous work has identified protein targets for HNE alkylation, the sequence specificity of alkylation and dynamics in a cellu...
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| 發表在: | Anal Chem |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American
Chemical
Society
2015
|
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350606/ https://ncbi.nlm.nih.gov/pubmed/25654326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac504685y |
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