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Prefibrillar Tau Oligomers in MCI and Alzheimer Disease

BACKGROUND: AD (Alzheimer’s disease) is a progressive neurodegenerative disorder characterized by the accumulation of extracellular amyloid β-peptide and intracellular tau. Here we review data suggesting that pre-fibrillar tau oligomers mediate cognitive decline early in the disease. OBJECTIVE: To s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mufson, Elliott J., Ward, Sarah, Binder, Lester
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151109/
https://ncbi.nlm.nih.gov/pubmed/24029627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000353687
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