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Prefibrillar Tau Oligomers in MCI and Alzheimer Disease
BACKGROUND: AD (Alzheimer’s disease) is a progressive neurodegenerative disorder characterized by the accumulation of extracellular amyloid β-peptide and intracellular tau. Here we review data suggesting that pre-fibrillar tau oligomers mediate cognitive decline early in the disease. OBJECTIVE: To s...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151109/ https://ncbi.nlm.nih.gov/pubmed/24029627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000353687 |
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