Progression of Tau Pathology in Cholinergic Basal Forebrain Neurons in Mild Cognitive Impairment and Alzheimer's Disease

Tau is a microtubule-associated protein that forms neurofibrillary tangles (NFTs) in the selective vulnerable long projection neurons of the cholinergic basal forebrain (CBF) in Alzheimer's disease (AD). Although CBF neurodegeneration correlates with cognitive decline during AD progression, lit...

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Главные авторы: Vana, Laurel, Kanaan, Nicholas M., Ugwu, Isabella C., Wuu, Joanne, Mufson, Elliott J., Binder, Lester I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2011
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204017/
https://ncbi.nlm.nih.gov/pubmed/21945902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.044
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