Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer’s disease

Endocytic system dysfunction is one of the earliest disturbances that occur in Alzheimer’s disease (AD), and may underlie the selective vulnerability of cholinergic basal forebrain (CBF) neurons during the progression of dementia. Herein we report that genes regulating early and late endosomes are s...

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Autori principali: Ginsberg, Stephen D., Mufson, Elliott J., Alldred, Melissa J., Counts, Scott E., Wuu, Joanne, Nixon, Ralph A., Che, Shaoli
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163754/
https://ncbi.nlm.nih.gov/pubmed/21669283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchemneu.2011.05.012
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