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Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease
Although tau is the primary constituent of neurofibrillary tangles (NFTs), evidence suggests that its toxic moiety is oligomeric in Alzheimer disease (AD). In this regard, tau oligomers correlate more strongly with neuronal loss than NFTs and exhibit neurotoxicity in preclinical AD models. Here, we...
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| Publicado no: | J Neuropathol Exp Neurol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251641/ https://ncbi.nlm.nih.gov/pubmed/29378005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlx120 |
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