Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

Cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons display neurofibrillary tangles (NFTs) during Alzheimer's disease (AD) progression, yet the mechanisms underlying this selective vulnerability are currently unclear. Rac1, a member of the Rho family of GTPases, may interact with the...

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Bibliografische gegevens
Hoofdauteurs: Perez, Sylvia E., Getova, Damianka P., He, Bin, Counts, Scott E., Geula, Changiz, Desire, Laurent, Coutadeur, Severine, Peillon, Helene, Ginsberg, Stephen D., Mufson, Elliott J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2012
Onderwerpen:
Regular Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349868/
https://ncbi.nlm.nih.gov/pubmed/22142809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.027
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