Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

Cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons display neurofibrillary tangles (NFTs) during Alzheimer's disease (AD) progression, yet the mechanisms underlying this selective vulnerability are currently unclear. Rac1, a member of the Rho family of GTPases, may interact with the...

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Bibliografski detalji
Glavni autori: Perez, Sylvia E., Getova, Damianka P., He, Bin, Counts, Scott E., Geula, Changiz, Desire, Laurent, Coutadeur, Severine, Peillon, Helene, Ginsberg, Stephen D., Mufson, Elliott J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2012
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349868/
https://ncbi.nlm.nih.gov/pubmed/22142809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.027
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