Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

Cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons display neurofibrillary tangles (NFTs) during Alzheimer's disease (AD) progression, yet the mechanisms underlying this selective vulnerability are currently unclear. Rac1, a member of the Rho family of GTPases, may interact with the...

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Detalhes bibliográficos
Main Authors: Perez, Sylvia E., Getova, Damianka P., He, Bin, Counts, Scott E., Geula, Changiz, Desire, Laurent, Coutadeur, Severine, Peillon, Helene, Ginsberg, Stephen D., Mufson, Elliott J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349868/
https://ncbi.nlm.nih.gov/pubmed/22142809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.027
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