Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

Cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons display neurofibrillary tangles (NFTs) during Alzheimer's disease (AD) progression, yet the mechanisms underlying this selective vulnerability are currently unclear. Rac1, a member of the Rho family of GTPases, may interact with the...

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Bibliographische Detailangaben
Hauptverfasser: Perez, Sylvia E., Getova, Damianka P., He, Bin, Counts, Scott E., Geula, Changiz, Desire, Laurent, Coutadeur, Severine, Peillon, Helene, Ginsberg, Stephen D., Mufson, Elliott J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2012
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349868/
https://ncbi.nlm.nih.gov/pubmed/22142809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.027
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