Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer’s disease

Cholinergic basal forebrain neurons of the nucleus basalis of Meynert (nbM) regulate attentional and memory function and are exquisitely prone to tau pathology and neurofibrillary tangle (NFT) formation during the progression of Alzheimer’s disease (AD). nbM neurons require the neurotrophin nerve gr...

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Bibliografske podrobnosti
izdano v:Neurobiol Dis
Main Authors: Tiernan, Chelsea T., Ginsberg, Stephen D., He, Bin, Ward, Sarah M., Guillozet-Bongaarts, Angela L., Kanaan, Nicholas M., Mufson, Elliott J., Counts, Scott E.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278831/
https://ncbi.nlm.nih.gov/pubmed/29859871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.05.021
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