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Engineering the elongation factor Tu for efficient selenoprotein synthesis

Selenocysteine (Sec) is naturally co-translationally incorporated into proteins by recoding the UGA opal codon with a specialized elongation factor (SelB in bacteria) and an RNA structural signal (SECIS element). We have recently developed a SECIS-free selenoprotein synthesis system that site-specif...

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Hlavní autoři: Haruna, Ken-ichi, Alkazemi, Muhammad H., Liu, Yuchen, Söll, Dieter, Englert, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150793/
https://ncbi.nlm.nih.gov/pubmed/25064855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku691
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