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The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

Viral RNA-dependent RNA polymerases (RdRps) responsible for the replication of single-strand RNA virus genomes exert their function in the context of complex replication machineries. Within these replication complexes the polymerase activity is often highly regulated by RNA elements, proteins or oth...

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Bibliografiske detaljer
Main Authors: Potisopon, Supanee, Priet, Stéphane, Collet, Axelle, Decroly, Etienne, Canard, Bruno, Selisko, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191377/
https://ncbi.nlm.nih.gov/pubmed/25209234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku666
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