The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

Viral RNA-dependent RNA polymerases (RdRps) responsible for the replication of single-strand RNA virus genomes exert their function in the context of complex replication machineries. Within these replication complexes the polymerase activity is often highly regulated by RNA elements, proteins or oth...

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Detalhes bibliográficos
Main Authors: Potisopon, Supanee, Priet, Stéphane, Collet, Axelle, Decroly, Etienne, Canard, Bruno, Selisko, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191377/
https://ncbi.nlm.nih.gov/pubmed/25209234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku666
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