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An RNA cap (nucleoside-2′-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

Viruses represent an attractive system with which to study the molecular basis of mRNA capping and its relation to the RNA transcription machinery. The RNA-dependent RNA polymerase NS5 of flaviviruses presents a characteristic motif of S-adenosyl-l-methionine-dependent methyltransferases at its N-te...

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Detalhes bibliográficos
Main Authors: Egloff, Marie-Pierre, Benarroch, Delphine, Selisko, Barbara, Romette, Jean-Louis, Canard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125380/
https://ncbi.nlm.nih.gov/pubmed/12032088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2757
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