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Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA copy according to Watson-Crick base-pairing ru...

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Bibliografiska uppgifter
I publikationen:Viruses
Huvudupphovsmän: Selisko, Barbara, Papageorgiou, Nicolas, Ferron, François, Canard, Bruno
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850366/
https://ncbi.nlm.nih.gov/pubmed/29385764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10020059
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