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Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases
Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA copy according to Watson-Crick base-pairing ru...
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Publicado no: | Viruses |
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Principais autores: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850366/ https://ncbi.nlm.nih.gov/pubmed/29385764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10020059 |
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