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Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA copy according to Watson-Crick base-pairing ru...

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Detalhes bibliográficos
Publicado no:Viruses
Principais autores: Selisko, Barbara, Papageorgiou, Nicolas, Ferron, François, Canard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850366/
https://ncbi.nlm.nih.gov/pubmed/29385764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10020059
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