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Engineering the elongation factor Tu for efficient selenoprotein synthesis
Selenocysteine (Sec) is naturally co-translationally incorporated into proteins by recoding the UGA opal codon with a specialized elongation factor (SelB in bacteria) and an RNA structural signal (SECIS element). We have recently developed a SECIS-free selenoprotein synthesis system that site-specif...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150793/ https://ncbi.nlm.nih.gov/pubmed/25064855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku691 |
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