A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...

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Hlavní autoři: Sun, Jingnan, Li, Wei, Sun, Yunpeng, Yu, Dehai, Wen, Xue, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Hoffman, Andrew R., Hu, Ji-Fan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150754/
https://ncbi.nlm.nih.gov/pubmed/25092925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku549
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