A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...

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Détails bibliographiques
Auteurs principaux: Sun, Jingnan, Li, Wei, Sun, Yunpeng, Yu, Dehai, Wen, Xue, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Hoffman, Andrew R., Hu, Ji-Fan
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Gene regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150754/
https://ncbi.nlm.nih.gov/pubmed/25092925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku549
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