A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...

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Bibliografiske detaljer
Main Authors: Sun, Jingnan, Li, Wei, Sun, Yunpeng, Yu, Dehai, Wen, Xue, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Hoffman, Andrew R., Hu, Ji-Fan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150754/
https://ncbi.nlm.nih.gov/pubmed/25092925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku549
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