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A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies
Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150754/ https://ncbi.nlm.nih.gov/pubmed/25092925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku549 |
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