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A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...

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Detalhes bibliográficos
Main Authors: Sun, Jingnan, Li, Wei, Sun, Yunpeng, Yu, Dehai, Wen, Xue, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Hoffman, Andrew R., Hu, Ji-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150754/
https://ncbi.nlm.nih.gov/pubmed/25092925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku549
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