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Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus
Kcnq1ot1 is a long noncoding ribonucleic acid (RNA; lncRNA) that participates in the regulation of genes within the Kcnq1 imprinting domain. Using a novel RNA-guided chromatin conformation capture method, we demonstrate that the 5′ region of Kcnq1ot1 RNA orchestrates a long-range intrachromosomal lo...
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| Glavni autori: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882787/ https://ncbi.nlm.nih.gov/pubmed/24395636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201304152 |
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