Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus

Kcnq1ot1 is a long noncoding ribonucleic acid (RNA; lncRNA) that participates in the regulation of genes within the Kcnq1 imprinting domain. Using a novel RNA-guided chromatin conformation capture method, we demonstrate that the 5′ region of Kcnq1ot1 RNA orchestrates a long-range intrachromosomal lo...

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Detalhes bibliográficos
Main Authors: Zhang, He, Zeitz, Michael J., Wang, Hong, Niu, Beibei, Ge, Shengfang, Li, Wei, Cui, Jiuwei, Wang, Guanjun, Qian, Guanxiang, Higgins, Michael J., Fan, Xianqun, Hoffman, Andrew R., Hu, Ji-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882787/
https://ncbi.nlm.nih.gov/pubmed/24395636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201304152
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