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Pharmacophore-Based Virtual Screening and Biological Evaluation of Small Molecule Inhibitors for Protein Arginine Methylation

Protein arginine methyltransferases (PRMTs) are proved to play vital roles in chromatin remodeling, RNA metabolism and signal transduction. Aberrant regulation of PRMT activity is associated with various pathological states such as cancer and cardiovascular disorders. Development and application of...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Juxian, Chen, Limin, Sinha, Sarmistha Halder, Liang, Zhongjie, Cai, Huifang, Muniyan, Sakthivel, Chou, Yu-Wei, Yang, Chao, Li, Keqin Kathy, Lin, Ming-Fong, Jiang, Hualiang, Zheng, Yujun George, Luo, Cheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150255/
https://ncbi.nlm.nih.gov/pubmed/22928876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300521m
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