Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1

Arginine methylation is a common post-translational modification that is crucial in modulating gene expression at multiple critical levels. The arginine methyltransferases (PRMTs) are envisaged as promising druggable targets but their role in physiological and pathological pathways is far from being...

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Autors principals: Castellano, Sabrina, Spannhoff, Astrid, Milite, Ciro, Dal Piaz, Fabrizio, Cheng, Donghang, Tosco, Alessandra, Viviano, Monica, Yamani, Abdellah, Cianciulli, Agostino, Sala, Marina, Cura, Vincent, Cavarelli, Jean, Novellino, Ettore, Mai, Antonello, Bedford, Mark T., Sbardella, Gianluca
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508294/
https://ncbi.nlm.nih.gov/pubmed/23095008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301097p
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