Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1

Arginine methylation is a common post-translational modification that is crucial in modulating gene expression at multiple critical levels. The arginine methyltransferases (PRMTs) are envisaged as promising druggable targets but their role in physiological and pathological pathways is far from being...

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Detalhes bibliográficos
Main Authors: Castellano, Sabrina, Spannhoff, Astrid, Milite, Ciro, Dal Piaz, Fabrizio, Cheng, Donghang, Tosco, Alessandra, Viviano, Monica, Yamani, Abdellah, Cianciulli, Agostino, Sala, Marina, Cura, Vincent, Cavarelli, Jean, Novellino, Ettore, Mai, Antonello, Bedford, Mark T., Sbardella, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508294/
https://ncbi.nlm.nih.gov/pubmed/23095008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301097p
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