Pharmacophore-Based Virtual Screening and Biological Evaluation of Small Molecule Inhibitors for Protein Arginine Methylation

Protein arginine methyltransferases (PRMTs) are proved to play vital roles in chromatin remodeling, RNA metabolism and signal transduction. Aberrant regulation of PRMT activity is associated with various pathological states such as cancer and cardiovascular disorders. Development and application of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wang, Juxian, Chen, Limin, Sinha, Sarmistha Halder, Liang, Zhongjie, Cai, Huifang, Muniyan, Sakthivel, Chou, Yu-Wei, Yang, Chao, Li, Keqin Kathy, Lin, Ming-Fong, Jiang, Hualiang, Zheng, Yujun George, Luo, Cheng
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150255/
https://ncbi.nlm.nih.gov/pubmed/22928876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300521m
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars