EGFR Modulates DNA Synthesis and Repair through Tyr Phosphorylation of Histone H4

Posttranslational modifications of histones play fundamental roles in many biological functions. Specifically, histone H4-K20 methylation is critical in DNA synthesis and repair. However, little is known about how these functions are regulated by the upstream stimuli. Here, we identify a tyrosine ph...

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Huvudupphovsmän: Chou, Ruey-Hwang, Wang, Ying-Nai, Hsieh, Yi-Hsien, Li, Long-Yuan, Xia, Weiya, Chang, Wei-Chao, Chang, Ling-Chu, Cheng, Chien-Chia, Lai, Chien-Chen, Hsu, Jennifer L., Chang, Wei-Jung, Chiang, Shu-Ya, Lee, Hong-Jen, Liao, Hsin-Wei, Chuang, Pei-Huan, Chen, Hui-Yu, Wang, Hung-Ling, Kuo, Sheng-Chu, Chen, Chung-Hsuan, Yu, Yung-Luen, Hung, Mien-Chie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149291/
https://ncbi.nlm.nih.gov/pubmed/25073158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.008
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